ALPHARONA prescribing Information (intranasal)

Pharmacological properties
ALPHARONA ® is a recombinant human interferon alpha-2b – protein synthesized by Escherichia coli strain whose genetic apparatus has the gene of human leukocytal interferon alpha-2b. Alpharona is similar to human leukocytal interferon alpha-2b. It has immunostimulating, antiviral, antiinflammatory and antimicrobial activity.
Indications for use
Prevention and treatment of ARVI and influenza in adults and children at initial stages of the disease.
Individual intolerance of interferon drugs, severe forms of allergic diseases.
Dosing and Administration

Intranasally. Dissolve the vial content in 5 ml of water for injections.

In case of first signs of influenza or ARVI: for adults — 3 drops into each nasal passage 5–6 times a day (single dose — 3000 IU, daily dose— 15000–18000 IU), newborns and children younger than 1 year old — 1 drop 5 times a day (single dose - 1000 IU, daily dose — 5000 IU), children from 1 to 3 years old — 2 drops 3–4 times a day (single dose — 2000 IU, daily dose — 6000–8000 IU), from 3 to 14 years old — 2 drops 4–5 times a day (single dose — 2000 IU, daily dose — 8000–10000 IU) for 5 days.

For prevention of ARVI and influenza:

In case of contact with sick person and/or exposure to cold: in accordance with age-dependent dosage, twice a day for 5-7 days. If necessary, preventive course may be repeated. In case of single contact, one dripping is enough.

In case of seasonal rise of morbidity, in accordance with age-dependent dosage in the morning every second or third day.

It is recommended to massage the nose alae with fingers for a few minutes after dripping in order to distribute the drug in nasal cavity evenly.

Side effects
None known.
Form of issue
Lyophilizate for preparation of solution for intranasal administration of 50000 IU.
Storage conditions and shelf life
Keep in dry dark place at a temperature of +10°С maximum. Shelf life - 2 years. Keep the drug solution in refrigerator for not longer than 10 days (do not freeze). Do not use after expiry date.


Legal address:
30/34 Chekhov street, Serpukhov, Moscow region, Russia, 142200

Мanufacturer's address:
Biomed named after Mechnikov, Petrovo-Dalnee, Krasnogorsk district, Moscow region, Russia, 143422

Phone/fax:+7 (4967) 36-07-71, +7 (495) 120-12-47


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